pain abdomen secondary to uncontrolled sugars with DKA with ? pancreatitis with AKI on CKD. (CKD secondary to metabolic acidosis ) with HFPEF( EF- 58%) with metabolic acidosis secondary to DKA & CKD with H/o DM-2 , hypothyroidism , CKD

43 year female came with complaints of pain abdomen & vomitings since 1 day


HOPI : 

Patient was apparently asymptomatic 6 yrs back, then had anasarca , went to hospital in hyderabad & diagnosed to have 
hypothyroidism ( started on tab.THYRONORM 50 micrograms) 
& also diagnosed as 
renal failure & was on TAB.TORSEMIDE 20MG+ SPIRONOLACTONE 50MG
& also DM 2 ( started on inj.MIXTARD 6U....X...10U & increased doses of MIXTARD to 20U...X...25U since 1 1/2 yr. 

Currently patient complaining of pain abdomen which is diffuse , intermittent, dull aching pain associated with vomitings, 2 episodes non bilious , non projectile , food as content . 
No H/O fever, cold, cough, loose stools, constipation , malena, haematuria
No H/O pedal edema, decreased urine output, facial puffiness, 



PAST HISTORY :  

k/c/o DM 2 since 6yrs ( using INJ.MIXTARD 20U...X....25U) 

Hypothyroidism since 6yrs ( TAB.THYRONORM 25microgram)

N/k/c/o of HTN, bronchial asthma, epilepsy, tb



TREATMENT HISTORY :

 1) DM 2 since 6yrs ( using INJ.MIXTARD 20U...X....25U)


2)Hypothyroidism since 6yrs ( TAB.THYRONORM 25microgram)


PERSONAL HISTORY : 

Diet : mixed 
Appetite : decreasd since 6 yrs 
Sleep : adequate 
Bowel & bladder  : regular 
No known addictions.


FAMILY HISTORY : Not significant



ON EXAMINATION : 

Patient  is conscious, coherent, cooperative. 

Pallor + 

Icterus,clubbing, cyanosis ,  koilonychia, edema are absent


VITALS 
Temp- Afebrile 
Bp-150/80 mm hg
Pr- 88bpm
Rr-21cpm
Spo2- 99% on RA
Grbs : High



SYSTEMIC EXAMINATION : 


RS-  decreased breath sounds on B/L IAA & ISA 

Cvs-S1 S2 +

P/A - soft,  diffuse tenderness + 

Cns-   NAD 
GCS - 15/15



INVESTIGATIONS : (3/2/22)
ABG : 
PH - 7.21
PCO2- 25.8
PO2- 89.2
HCO3- 12

RBS : 560MG/DL
HBA1C : 8.1

HEMOGRAM : 
HB: 9.4
TLC : 13,200
RBC : 3.47million/cu3

Urine for ketone bodies : negative 

RFT :
sr cr : 4.6
Urea : 4.6
Na+ : 131
K+: 4.6

LFT : 
SGPT : 125
SGOT : 137
ALP : 372
TP: 5.5
ALB : 2.7

Sr. Amylase : 237
Sr. Lipase : 92

USG ABDOMEN : 
1.GB wall edema
2.Right mild pleural effusion 
3.No ascitis











Xray erect abdomen on 5/2/22


chest x- ray on 5/2/22





Review usg on 5/2/22



PROVISIONAL DIAGNOSIS :    pain abdomen secondary to uncontrolled sugars with DKA with ?  pancreatitis with AKI on CKD. (CKD secondary to metabolic acidosis ) with HFPEF(EF- 58%) with metabolic acidosis secondary to DKA & CKD with H/o DM-2 , hypothyroidism  , CKD

TREATMENT PLAN: 



ON 3/2/22
1)IVF –  0.9%NS 1L FOR 1ST hour 
                              1L FOR 2ND hour 
                              1L FOR 3rd hour   
2) IVF – 0.9% NS @ 250ml/hr for next 6 hours 
3)INJ. HAI – 0.1IU /KG /B.wt  IV /STAT 
 4)INJ.HAI – 1ml in 39ml NS @ 6ml/hr infusion (according to ALGO 1  )
5 INJ. PANTOP 40mg IV/OD
6)INJ.ZOFER 4mg IV/SOS

TREATMENT ON 4/2/22 & 5/2/22
1)  IVF – 0.9% NS @ 150ml/hr

2) INJ. PANTOP 40mg IV/OD
3)INJ.ZOFER 4mg IV/TID 
4) INJ. METROGYL 500MG /IV / TID
5) INJ. TRAMADOL 1AMP IN 100 ML NS /IV/TID 
6)INJ. INSULIN INFUSION WITH 2ML/HR 
7)INJ.BUSCOPAN 2CC IV/SOS
8)INJ.LASIX 40MG IV/BD
9) TAB.THYRONORM 50microgram PO/OD

10)  PLANNING TO SEND STOOL FOR OVA CYST & CULTURE( i/v/o yellowish green stools ) 







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