55 yr female with involuntary movements

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January 21,2022

55 YR OLD FEMALE WITH DEPRESSION AND INVOLUNTARY MOVEMENTS



A 55 years old female came to the GM OPD with chief complaints of 

 - sudden onset of tremors in right arm since yesterday which stopped during sleep and started again in the morning. 


 


History of present illness: 

She was apparently asymptomatic 1year ago. Then as she developed abnormal behaviour with suspicion over that they are harming her and fearfulness towards others 1yr back after her sister's husband died due to excessive alcohol intake daily.

Later past 6 months visited psychiatry op with complaints of self smiling,self talking,decreased response,decrease speech output, difficulty to speak with decreased self care and hygiene,not doing any household work, not interacting with others,decreased eye contact,visual and auditory hallucinations diagnosed as psychosis and medication risperidone.

She didn't follow up and went to nalgonda 3months back CT and MRI scans were taken and were normal. Medication was given which she used for 2days and stopped themselves as she was not improving. 

3days back again went to nalgonda were she was given T.olanzapine and T.quetiapine. Yesterday sudden onset of involuntary movements in right arm while eating stopped during sleep and continued next day morning.







Past history: She is suffering from asthma since childhood. 


No  DM, HTN, TB, Epilepsy, CAD.


 Family h/o: her relative experienced same symptoms in the past.


Personal h/o: 


Diet -mixed 


Appetite - normal 


Bowel habits - regular 


Bladder habits - regular


Sleep - adequate 


No addictions 


She is  married and have 2daughters and 1son .she had disputes in her family.


General examination: Patient is conscious, coherent,noncooperative ,well built and well nourished.


No pallor,icterus, cyanosis, clubbing, lymphadenopathy, Edema.


Vitals: 


Pulse rate - 94 bpm 


Temperature- 98.2  degree Fahrenheit 


RR - 15 cpm 


BP - 130/90 mmHg 


Systemic examination : 


CVS : S1 S2 + , no added murmurs 


RS :BAE + ,NVBS heard 


P/A :soft , non tender 


        No organomegaly 


        No distension 


        Bowel sounds heard


CNS:



Pupils- B/L dilated, reacting to light 


Tone-               Rt.                          Lt.


          UL         N                            N


          LL          N                            N


Power-


          UL         5/5                          5/5


          LL          5/5                         5/5


Reflexes-


          B-            +                           +


          T-            +                            +


          S-            +                            +


          K-           +                            +


          A-           +                            +


          P-       Flexor                    Flexor


Hand grip        100%.           100%





Provisional diagnosis

Psychosis? Depression?anxiety disorder?



Treatment:

1. Stop T.olanzapine T.quetiapine

2.Tab.tri hexi phenidyl (THP) 2mg

3.Tab mirtazepine

4. Tab. Clonazepam if patient is anxious or restless



To rule out extrapyramidal side effects of antipsychotic drugs- i.m promethazine challenge test was done 
Symptoms were slightly reduced according to patient 



Summary














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